This is a study I did of the human face/skin, most of the details were created from scratch using Blender and Substance Painter. I've sculpted the skin details using the default Blender's brushes, no alphas projection. The skin texture was created in SP, the eyes and the teeth the texture of those were done inside Blender, using procedural textures. Render in Cycles using one Plane with Emission shader and Pro Lighting Skies.
If you want to take a close look on the file, you can download it at the link below.